Healthcare is a major contributor to the economy in South Carolina, especially in the Charleston region. The sector not only provides essential medical services but also plays a key role in job creation and business development.
The South Carolina Hospital Association reports that hospitals across the state have an economic impact of more than $36.7 billion and support over 203,000 jobs. Each dollar spent by hospitals generates an additional $0.90 within the broader economy, nearly doubling its value as it circulates through local businesses and industries. Recent rankings place South Carolina 10th for healthcare quality and 13th for hospital quality nationally, according to U.S. News & World Report.
Four main healthcare systems operate in the Charleston area: MUSC, Roper St. Francis Healthcare, Novant Health, and Trident Health. These organizations bring different strengths to the community while contributing to economic growth.
MUSC has an annual statewide economic impact of $10.1 billion and supports more than 52,000 jobs. In the Charleston Tri-county area alone, MUSC accounts for $7.5 billion in impact and nearly 38,380 jobs. The institution’s research, education, and clinical operations create additional employment opportunities beyond direct healthcare roles.
Roper St. Francis Healthcare is building a new North Charleston campus that is expected to generate $2.5 billion in economic activity and create 3,600 jobs once completed.
Novant Health contributed $1.2 billion in total economic impact across South Carolina in 2024 and supported almost 5,000 jobs statewide; within Charleston specifically it generated over 2,200 jobs and $540 million in output along with significant tax revenues at all levels of government.
Trident Health employs more than 3,500 people locally while serving over 367,000 patients each year; its recent investments include over $335 million toward salaries as well as capital improvements and charity care initiatives.
Each system’s approach—whether focused on academic medicine or expanding access—helps ensure that healthcare infrastructure remains strong amid population growth and changing needs throughout the region.
“Healthcare is far more than a service people turn to in moments of need,” said a spokesperson from the Charleston Metro Chamber of Commerce. “It is a cornerstone of South Carolina’s economy and a driver of growth across the Charleston region.”
The business community sees these health systems as important partners for regional prosperity due to their investments fueling job growth and consumer spending while supporting other industries such as construction or technology.
On August 26th, leaders from all four major health systems will participate in Impact: The Business of Healthcare—a panel discussion hosted by the Charleston Metro Chamber—to discuss future challenges facing both healthcare delivery and regional economic development.
